We treat certain forms of diseases related to bone, tendon, muscle, ligaments or other connective tissues. When assessing an injury or pathology, we look at the overall balance of the whole body in terms of dynamics of Qi flow and the causes of disease. For example, if we try to relieve only pain without considering such balancing then not only will the injury return, but also it can lead to other injuries soon or later. So it is important to dissect biomechanical deficiencies and determine where functional deficiencies are initiated and how those impairments are leading to symptoms or functional deficit. To this end, we strive to provide individualized care through integration of modern medicine and traditional oriental medicine.
Author: admin
1. Education & Employment
B.S/ M.S., Korea University, Seoul, Korea
Ph.D in Biochemistry, University of Illinois at Chicago, Chicago, IL
Research Scientist, California Institute of Technology Pasadena, CA
Assistant Adjunct Professor of Pharmacology, University of California San Diego, La Jolla, CA
M.S., Pacific College of Oriental Medicine, San Diego, CA
2. Licensing & Certification
California Licensed Acupuncturist (LAc)
Dipl. of Oriental Medicine (NCCAOM)
3. Selected Publications
1. Han, S.K., Kim, K.P., Koduri, R., Bittova, L., Munoz, N.M., Leff, A.R., Wilton, D.C., Gelb, M.H., and Cho, W. (1999) Roles of Trp31 in high membrane binding and proinflammatory activity of human group V phospholipase A2. J Biol Chem 274, 11881-11888.
2. Dong, X., Han, S.K., Zylka, M.J., Simon, M.I., and Anderson, D.J. (2001) A diverse family of GPCRs expressed in specific subsets of nociceptive sensory neurons. Cell 106, 619-632.
3. Han, S.K., Mancino, V., and Simon, M.I. (2006) Phospholipase cbeta 3 mediates the scratching response activated by the histamine h1 receptor on C-fiber nociceptive neurons. Neuron 52, 691-703.
4. Imamachi, N., Park, G., Lee, H., Anderson, D.J., and *Simon, M.I., Basbaum, A.I., and *Han, S.K. (2009) TRPV1-expressing primary afferents generate behavioral responses to pruritogens via multiple mechanisms. Proc Natl Acad Sci U S A 106, 11330 – 11335
5. Kim, D., You, B., Jo, E., Han, S.K., Simon, MI., and Lee, SJ. (2010) NADPH oxidase 2-derived reactive oxygen species in spinal cord microglia contribute to peripheral nerve injury-induced neuropathic pain. Proc Natl Acad Sci U S A 107, 14851 – 14856
6. Kim, S., Park, G., Kim, D., Lee, J., Min, H., Wall, E., Lee, C., *Simon, M.I., *Lee, SJ., and *Han, S.K. (2011) Analysis of cellular and behavioral responses to imiquimod reveals a unique itch pathway in TRPV1-expressing neurons. Proc Natl Acad Sci U S A 108, 3371 – 3376
7. *Han, S.K., and *Simon, MI (2011) Perspectives: Intracellular signaling and the origins of the sensations of itch and pain. Sci Signal 4, 38-41